Two of last year’s NFC playoff contenders square off in San Francisco on Thursday night as the New York Giants head west to take on the 49ers. The Giants gave up 60 unanswered points to start the 2023 regular season, losing at home to Dallas by a 40-0 score in Week 1 and finding themselves trailing in Phoenix by 20 at halftime. However, they roared back to beat the Cardinals, 31-28. The 49ers started their 2023 campaign with a 30-7 rout of the Steelers in Pittsburgh and followed that up with a 30-23 win over the Rams down in Los Angeles last week. The 49ers won their last meeting with the Giants, rolling to a 36-9 victory in New York in 2020. Let’s break down this midweek showdown as you start to plan your online betting for the weekend in this game between NFL Giants vs 49ers.
Week 2: NFL Giants vs 49ers TNF Betting Odds | Bet NFL Football Lines by Xbet Sportsbook
When: Thursday Night Football, September 21, 2023, 8:15 pm ET
Where: Levi’s stadium, Santa Clara, CA
TV: Prime Video
Radio: No National Broadcast
Live Stream: FuboTV
NFL Odds: San Francisco -10.5 / O/U 44 // San Francisco -600 / New York +430
Why should you bet on the Giants?
Even with that 1-1 start, the Giants find themselves still looking up at the rest of the NFC East, which has three unbeaten teams through two weeks for the first time in 34 years. The Giants’ offense took a while to wake up against the Cardinals, as they were down 28-14 going into the fourth quarter last week, but they stacked up 17 points in the last quarter, including the game-winning field goal with just 19 seconds remaining on the clock. They ended up outgaining the Cardinals, 439-379, and had two more first downs.
The big numbers on offense helped the Giants get out of the basement in a number of offensive categories, and they are now 13th in the NFL in rushing yardage but still 24th in passing yardage. Their scoring defense is still dead last, though, as they have permitted 68 points through two games. Daniel Jones has spent a lot of games running for his life, as he has taken 10 sacks through two games. The biggest problem for the Giants’ offense will be the absence of Saquon Barkley, who suffered an ankle injury against the Cardinals. It will be up to Matt Breida and Gary Brightwell to split the carries.
Bet on the Giants to Win Today
Why should you put your money on the 49ers?
The 49ers got a tougher challenge than they expected out of the Rams and trailed for most of the first half, drawing even as the second quarter ended on a one-yard sneak by Brock Purdy. The second half saw the 49ers build a 27-17 lead and hold at least a seven-point lead the rest of the game. The 49ers lost the yardage, time of possession and first-down battles but won the turnover margin, getting six points off two takeaways without committing any turnovers on their end.
The San Francisco rushing game ranks third in the league with 173.5 yards per game, led by Christian McCaffrey, who has 42 carries for 268 yards and a pair of touchdowns. Deebo Samuel continues to get some carries with seven attempts for 46 yards and a score. Samuel is also tied for the team lead with 11 catches, along with Brandon Aiyuk (172 receiving yards, 2 TD).
Bet on the 49ers to Win Today
NFL Giants vs 49ers Final Score and Prediction
The San Francisco defense has been stout all season, except for some off moments during the first half against the Rams. The Giants struggle to stop the pass rush, and the 49ers have a ferocious rush led by Nick Bosa. The absence of Saquon Barkley will make it even harder for the Giants to move the ball. I predict a final score of San Francisco 34, New York 13.
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